

@article {574,
	title = {Prevalence of rotavirus, adenovirus, norovirus, and astrovirus infections and coinfections among hospitalized children in northern France},
	journal = {Journal of Clinical Microbiology},
	volume = {48},
	number = {5},
	year = {2010},
	note = {Tran, Adissa Talmud, Deborah Lejeune, Benoit Jovenin, Nicolas Renois, Fanny Payan, Christopher Leveque, Nicolas Andreoletti, Laurent Research Support, Non-U.S. Gov{\textquoteright}t United States Journal of clinical microbiology},
	pages = {1943-6},
	type = {Journal Article},
	abstract = {<p>From January to December 2007, 973 stool specimens were prospectively collected from children hospitalized for gastroenteritis signs or from neonates and premature cases who were born in two French hospital settings in the north of France. They were tested by rapid enzyme immunoassay (EIA) analyses for rotavirus and adenovirus and by two commercially available ELISA tests for the detection of norovirus and astrovirus. The overall rates of prevalence for rotavirus, norovirus, adenovirus, and astrovirus were 21, 13, 5, and 1.8\%, respectively, and they did not significantly differ between the two hospital settings (P=0.12). Mixed virus infections were detected in 32 (3.3\%) of the 973 study children and were associated with norovirus in 21 (66\%) infants, including 5 premature cases. From fall to spring, norovirus infections accounted for 52\% of documented gastroenteritidis viral infections at a time when rotavirus was epidemic, resulting in mixed norovirus and rotavirus gastrointestinal tract infections. Of the 367 documented viral gastroenteritis cases, 15 (4.1\%) were identified as nosocomial infections, 5 of which occurred in premature cases. These findings highlight the need to implement norovirus and astrovirus ELISA detection assays in association with rapid EIA rotavirus and adenovirus detection assays for the clinical diagnosis and the nosocomial prevention of gastroenteritis viral infections in pediatric departments.</p>
},
	keywords = {Adenoviridae Infections/ epidemiology Astroviridae Infections/ epidemiology Caliciviridae Infections/ epidemiology Child, Hospitalized Child, Newborn Prevalence Rotavirus Infections/ epidemiology, Preschool Comorbidity Feces/virology France/epidemiology Gastroenteritis/ epidemiology Hospitalization Humans Immunoenzyme Techniques/methods Infant Infant},
	issn = {1098-660X (Electronic) 0095-1137 (Linking)},
	author = {Tran, A. and Talmud, D. and Lejeune, B. and Jovenin, N. and Renois, F. and Payan, C. and Leveque, N. and Andreoletti, L.}
}
