

@article {553,
	title = {Prevalence and molecular characterisation of human adenovirus in diarrhoeic children in Tanzania; a case control study},
	journal = {BMC Infect Dis},
	volume = {14},
	number = {1},
	year = {2014},
	note = {1471-2334 Moyo, Sabrina John Hanevik, Kurt Blomberg, Bjorn Kommedal, Oyvind Nordbo, Svein Arne Maselle, Samuel Langeland, Nina Journal Article England BMC Infect Dis. 2014 Dec 12;14(1):666. doi: 10.1186/s12879-014-0666-1.},
	pages = {666},
	type = {Journal Article},
	abstract = {{BACKGROUND: Human adenovirus (HAdV) causes acute diarrhoea sporadically, as well as in outbreaks. Understanding the prevalence and types of HAdV in diarrhoea is important for control and preventive measures, especially in the African region where there is a high burden of diarrhoeal disease. The present study assessed the prevalence, molecular characteristics, seasonality and associated clinical features of HAdV infection Tanzanian children below two years of age with and without diarrhoea between 2010-2011. METHODS: Stool specimens, demographic and clinical information were collected in 690 cases and 545 controls. All stool samples were screened for HAdV-antigen using ELISA. Positive samples subsequently underwent real-time PCR and sequencing for molecular typing. RESULTS: HAdV was detected in 37 children, corresponding to a prevalence of 3.5\% (24/690) in diarrhoeic and 2.4\% (13/545) in non-diarrhoeic children (P > 0.05). Among HAdV-infected children, the median age was significantly lower in diarrhoeic than in non-diarrhoeic children (10 vs. 14 months, P<0.001). More than half of HAdV infected (54.2\%) were dehydrated as compared to diarrhoeic children without HAdV (45.8\%},
	issn = {1471-2334},
	doi = {10.1186/s12879-014-0666-1},
	author = {Moyo, S. J. and Hanevik, K. and Blomberg, B. and Kommedal, O. and Nordbo, S. A. and Maselle, S. and Langeland, N.}
}
