

@article {548,
	title = {Diagnosis and treatment of adenovirus infection in immunocompromised patients},
	journal = {Expert Rev Anti Infect Ther},
	volume = {11},
	number = {10},
	year = {2013},
	note = {1744-8336 Matthes-Martin, Susanne Boztug, Heidrun Lion, Thomas Journal Article Review England Expert Rev Anti Infect Ther. 2013 Oct;11(10):1017-28. doi: 10.1586/14787210.2013.836964. Epub 2013 Sep 27.},
	pages = {1017-28},
	type = {Journal Article},
	abstract = {In immunocompromised patients, human adenovirus (HAdV) infections can cause life-threatening multiorgan disease. This review summarizes the incidence and risk factors of invasive human adenovirus infections in immunocompromised patients as well as the recently developed standards for diagnostic methods and strategies according to the predominant risk factors in adults and children. Recommendations for preemptive and therapeutic treatment strategies and the outcome in different risk groups are presented. Novel therapeutic approaches including CMX001, a new orally bioavailable lipid conjugate of cidofovir and the transfer of adenovirus-specific donor T cells in the context of allogeneic stem cell transplantation are discussed.},
	keywords = {Adenovirus Infections, Homologous Treatment Outcome Viral Load/drug effects, Human/*immunology Adult Antiviral Agents/*therapeutic use Child Cytosine/*analogs \& derivatives/therapeutic use Humans *Immunocompromised Host Incidence Organophosphonates/*therapeutic use Risk Factors *Stem Cell Transplantation T-Lymphocytes/cytology/im, Human/diagnosis/epidemiology/*immunology/*therapy Adenoviruses},
	issn = {1478-7210},
	doi = {10.1586/14787210.2013.836964},
	author = {Matthes-Martin, S. and Boztug, H. and Lion, T.}
}
