

@article {3945,
	title = {Full genomic analysis of rabbit rotavirus {G}3P[14] strain {N}5 in {China}: identification of a novel {VP}6 genotype.},
	journal = {Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
	volume = {12},
	number = {7},
	year = {2012},
	pages = {1567{\textendash}1576},
	abstract = {Group A rotaviruses \{\{\}(RVAs)\{\}\} are major pathogens associated with acute gastroenteritis in young children and in a wide variety of domestic animals. The full-length genome of a rabbit \{\{\}RVA\{\}\} strain, \{\{\}RVA/Rabbit-tc/CHN/N5/1992/G3P[14],\{\}\} showed a \{\{\}G3-P[14]-I17-R3-C3-M3-A9-N1-T1-E3-H2\{\}\} genomic configuration. A novel \{\{\}VP6\{\}\} genotype, I17, was confirmed by the Rotavirus Classification Working Group. Phylogenetic analyses revealed that strain N5 possessed \{\{\}VP1-3,\{\}\} \{\{\}VP7,\{\}\} \{\{\}NSP1-2\{\}\} and \{\{\}NSP4\{\}\} genes closely related to those of the simian strain \{\{\}TUCH,\{\}\} \{\{\}NSP3\{\}\} and \{\{\}NSP5\{\}\} genes closely related to the human strains Wa and \{\{\}69M,\{\}\} and a \{\{\}VP4\{\}\} gene closely related to the rabbit strain 30/96 and sheep strain \{\{\}OVR762.\{\}\} The \{\{\}RRV\{\}\} and \{\{\}TUCH\{\}\} shared their ancestry with canine/feline \{\{\}RVAs\{\}\} and showed a close relationship to the human T152/feline-like \{\{\}RVAs.\{\}\} Comparison with the genotypes of the simian strains \{\{\}TUCH\{\}\} and \{\{\}RRV,\{\}\} canine strains A79-10, \{\{\}CU-1,\{\}\} K9, feline strains Cat2 and Cat97, and human strains T152 and \{\{\}69M\{\}\} showed that \{\{\}RVA/Rabbit-tc/CHN/N5/1992/G3P[14]\{\}\} was possibly of feline/canine origin, or was a multiple reassortment involving canine, feline and human rotaviruses. The sequencing and phylogenetic analyses of rotavirus genomes is critical to the elucidation of the patterns of virus evolution.},
	doi = {10.1016/j.meegid.2012.06.010},
	url = {http://dx.doi.org/10.1016/j.meegid.2012.06.010},
	author = {Guo, Dongchun and Liu, Jiasen and Lu, Yan and Sun, Yan and Yuan, Dongwei and Jiang, Qian and Lin, Huan and Li, Changwen and Si, Changde and Qu, Liandong}
}
