

@article {3138,
	title = {Polycystic echinococcosis in the state of {Acre}, {Brazil}: contribution to patient diagnosis, treatment and prognosis},
	journal = {Mem{\'o}rias Do Instituto Oswaldo Cruz},
	volume = {108},
	number = {5},
	year = {2013},
	month = {aug},
	pages = {533{\textendash}540},
	abstract = {The lack of knowledge regarding polycystic hydatid disease results in delayed or even incorrect diagnosis. The lack of systematic information regarding treatment also makes it difficult to assess the results and prognosis in patients with peritoneal and hepatic lesions caused by Echinococcus vogeli. Here we describe the clinical features of patients, propose a radiological classification protocol and describe a therapeutic option for the treatment of hydatid disease that previously had only been used for cases of cystic echinococcosis (Echinococcus granulosus). A prospective cohort study was initiated in 1999 and by 2009 the study included 60 patients. These patients were classified according to the PNM classification (parasite lesion, neighbouring organ invasion and metastases) and placed in one of three therapeutic modalities: (i) chemotherapy with albendazole at a dose of 10 mg/kg/day, (ii) surgical removal of cysts or (iii) percutaneous puncture of the cysts via puncture, aspiration, injection and re-aspiration (PAIR). The results were stratified according to therapeutic outcome: "cure", "clinical improvement", "no improvement", "death" or "no information". The PNM classification was useful in indicating the appropriate therapy in cases of polycystic hydatid disease. In conclusion, surgical therapy produced the best clinical results of all the therapies studied based on "cure" and "clinical improvement" outcomes. The use of PAIR for treatment requires additional study.},
	keywords = {80 and over, Adult, Aged, albendazole, Animals, Anticestodal Agents, Brazil, Cohort Studies, Dogs, Echinococcosis, Female, Humans, Male, Middle Aged, Prospective Studies, Severity of Illness Index, Tomography, X-Ray Computed, Young Adult},
	issn = {1678-8060},
	author = {Siqueira, Nilton Ghiotti de and Siqueira, Cl{\'a}udia Maria Villar Maziero de and Rodrigues-Silva, Ros{\^a}ngela and Soares, Manoel do Carmo P. and P{\'o}voa, Marinete Marins}
}
