

@article {3065,
	title = {Long-term results of hepatectomy for patients with alveolar echinococcosis: a single-center experience},
	journal = {Journal of the American College of Surgeons},
	volume = {212},
	number = {5},
	year = {2011},
	month = {may},
	pages = {804{\textendash}812},
	abstract = {BACKGROUND: Hepatectomy is the first-line treatment for alveolar echinococcosis (AE) if complete resection is feasible. However, a strategy for the treatment of patients with AE in whom the tumor cannot be resected completely remains to be defined. STUDY DESIGN: Data were retrospectively collected from 188 consecutive patients between 1984 and 2009. Overall survival (OS), progression-free survival (PFS), and risk factors were analyzed in patients classified into 3 groups (group A: complete resection, group B: reduction surgery, and group C: drainage or exploratory laparotomy). RESULTS: In group A (n = 119), the 10-, 15-, and 20-year OS was 98.9\%. In group B (n = 63), the 10-, 15-, and 20-year OS was 97.1\%, 92.8\%, and 61.9\%. In group C (n = 6), the 10- and 15-year OS was 50.0\% and 33.3\%. Patients in groups A and B had better prognoses than those in group C (p {\textbackslash}textless 0.001). In group A, the 10-, 15-, and 20-year PFS was 96.5\%, 94.4\%, and 94.4\%. In group B, the 10-, 15-, and 20-year PFS was 87.1\%, 71.6\%, and 61.4\%. In group C, the 10- and 15-year PFS was 50.0\% and 33.3\%. Patients in group A had better PFS than those in groups B and C (p {\textbackslash}textless 0.001). Curability was the only independent factor for both OS and PFS by multivariate analysis. CONCLUSIONS: Although the most effective therapy for AE is complete resection, a better prognosis can be achieved by reduction surgery and/or adjuvant albendazole therapy for patients with AE that cannot be completely resected.},
	keywords = {Analysis of Variance, Anticestodal Agents, Blotting, Echinococcosis, Enzyme-Linked Immunosorbent Assay, Female, Hepatectomy, Hepatic, Humans, Male, Middle Aged, Prognosis, Proportional Hazards Models, Retrospective Studies, Risk Factors, Survival Rate, Treatment Outcome, Western},
	issn = {1879-1190},
	doi = {10.1016/j.jamcollsurg.2011.02.007},
	author = {Kawamura, Norio and Kamiyama, Toshiya and Sato, Naoki and Nakanishi, Kazuaki and Yokoo, Hideki and Kamachi, Hirofumi and Tahara, Munenori and Yamaga, Shoji and Matsushita, Michiaki and Todo, Satoru}
}
