

@article {2389,
	title = {{Hemorrhagic colitis associated with a rare Escherichia coli serotype.}},
	journal = {The New England Journal of Medicine},
	volume = {308},
	number = {12},
	year = {1983},
	month = {mar},
	pages = {681{\textendash}5},
	abstract = {<p>We investigated two outbreaks of an unusual gastrointestinal illness that affected at least 47 people in Oregon and Michigan in February through March and May through June 1982. The illness was characterized by severe crampy abdominal pain, initially watery diarrhea followed by grossly bloody diarrhea, and little or no fever. It was associated with eating at restaurants belonging to the same fast-food restaurant chain in Oregon (P less than 0.005) and Michigan (P = 0.0005) and with eating any of three sandwiches containing three ingredients in common (beef patty, rehydrated onions, and pickles). Stool cultures did not yield previously recognized pathogens. However, a rare Escherichia coli serotype, O157:H7, that was not invasive or toxigenic by standard tests was isolated from 9 of 12 stools collected within four days of onset of illness in both outbreaks combined, and from a beef patty from a suspected lot of meat in Michigan. The only known previous isolation of this serotype was from a sporadic case of hemorrhagic colitis in 1975. This report describes a clinically distinctive gastrointestinal illness associated with E. coli O157:H7, apparently transmitted by undercooked meat.</p>
},
	keywords = {Adolescent, Adult, Aged, Child, Colitis, Colitis: etiology, Diarrhea, Diarrhea: etiology, Disease Outbreaks, Escherichia coli, Escherichia coli Infections, Escherichia coli Infections: epidemiology, Escherichia coli: classification, Female, Foodborne Diseases, Foodborne Diseases: epidemiology, Foodborne Diseases: etiology, Gastrointestinal Hemorrhage, Gastrointestinal Hemorrhage: etiology, Humans, Male, Meat, Meat: poisoning, Michigan, Middle Aged, Oregon},
	issn = {0028-4793},
	doi = {10.1056/NEJM198303243081203},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/6338386},
	author = {Riley, L W and Remis, R S and Helgerson, S D and McGee, H B and Wells, J G and Davis, B R and Hebert, R J and Olcott, E S and Johnson, L M and Hargrett, N T and Blake, P A and Cohen, M L}
}
