

@article {1878,
	title = {Inactivation of viruses on surfaces by ultraviolet germicidal irradiation},
	journal = {J Occup Environ Hyg},
	volume = {4},
	number = {6},
	year = {2007},
	note = {Tseng, Chun-Chieh Li, Chih-Shan eng Comparative Study Research Support, Non-U.S. Gov{\textquoteright}t 2007/05/03 09:00 J Occup Environ Hyg. 2007 Jun;4(6):400-5.},
	pages = {400-5},
	type = {Journal Article},
	abstract = {In many outbreaks caused by viruses, the transmission of the agents can occur through contaminated environmental surfaces. Because of the increasing incidence of viral infections, there is a need to evaluate novel engineering control methods for inactivation of viruses on surfaces. Ultraviolet germicidal irradiation (UVGI) is considered a promising method to inactivate viruses. This study evaluated UVGI effectiveness for viruses on the surface of gelatin-based medium in a UV exposure chamber. The effects of UV dose, viral nucleic acid type (single-stranded RNA, ssRNA; single-stranded DNA, ssDNA; double-stranded RNA, dsRNA; and double-stranded DNA, dsDNA), and relative humidity on the virus survival fraction were investigated. For 90\% viral reduction, the UV dose was 1.32 to 3.20 mJ/cm2 for ssRNA, 2.50 to to 4.47 mJ/cm2 for ssDNA, 3.80 to 5.36 mJ/cm2 for dsRNA, and 7.70 to 8.13 mJ/cm2 for dsDNA. For all four tested viruses, the UV dose for 99\% viral reduction was 2 times higher than those for 90\% viral reduction. Viruses on a surface with single-stranded nucleic acid (ssRNA and ssDNA) were more susceptible to UV inactivation than viruses with double-stranded nucleic acid (dsRNA and dsDNA). For the same viral reduction, the UV dose at 85\% relative humidity (RH) was higher than that at 55\% RH. In summary, results showed that UVGI was an effective method for inactivation of viruses on surfaces.},
	keywords = {Bacteriophage T7/physiology/*radiation effects Bacteriophage phi 6/physiology/*radiation effects Bacteriophage phi X 174/physiology/*radiation effects DNA, Double-Stranded/radiation effects RNA, Single-Stranded/radiation effects DNA, Viral/radiation effects *Ultraviolet Rays Virus Inactivation/radiation effects, Viral/radiation effects Escherichia coli/virology Humidity Levivirus/physiology/*radiation effects Pseudomonas syringae/virology RNA},
	issn = {1545-9624 (Print) 1545-9624 (Linking)},
	doi = {10.1080/15459620701329012},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/17474029},
	author = {Tseng, C. C. and Li, C. S.}
}
