

@article {1793,
	title = {Metagenomics: genomic analysis of microbial communities},
	journal = {Annu Rev Genet},
	volume = {38},
	year = {2004},
	note = {Riesenfeld, Christian S Schloss, Patrick D Handelsman, Jo eng Review 2004/12/01 09:00 Annu Rev Genet. 2004;38:525-52.},
	pages = {525-52},
	type = {Journal Article},
	abstract = {Uncultured microorganisms comprise the majority of the planet{\textquoteright}s biological diversity. Microorganisms represent two of the three domains of life and contain vast diversity that is the product of an estimated 3.8 billion years of evolution. In many environments, as many as 99\% of the microorganisms cannot be cultured by standard techniques, and the uncultured fraction includes diverse organisms that are only distantly related to the cultured ones. Therefore, culture-independent methods are essential to understand the genetic diversity, population structure, and ecological roles of the majority of microorganisms. Metagenomics, or the culture-independent genomic analysis of an assemblage of microorganisms, has potential to answer fundamental questions in microbial ecology. This review describes progress toward understanding the biology of uncultured Bacteria, Archaea, and viruses through metagenomic analyses.},
	keywords = {Archaea/*genetics Bacteria/*genetics Bacteriophages/*genetics Biodiversity *Environmental Microbiology Gene Library Genome, Archaeal *Genome, Bacterial Genomic Library Microscopy Phylogeny Rhodopsin/genetics Sequence Analysis},
	issn = {0066-4197 (Print) 0066-4197 (Linking)},
	doi = {10.1146/annurev.genet.38.072902.091216},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/15568985},
	author = {Riesenfeld, C. S. and Schloss, P. D. and Handelsman, J.}
}
