

@article {1578,
	title = {Quantitative detection of hepatitis a virus and enteroviruses near the United States-Mexico border and correlation with levels of fecal indicator bacteria},
	journal = {Applied and Environmental Microbiology},
	volume = {72},
	number = {12},
	year = {2006},
	note = {Gersberg, Richard M Rose, Michael A Robles-Sikisaka, Refugio Dhar, Arun K eng Evaluation Studies Research Support, Non-U.S. Gov{\textquoteright}t Research Support, U.S. Gov{\textquoteright}t, Non-P.H.S. 2006/09/19 09:00 Appl Environ Microbiol. 2006 Dec;72(12):7438-44. Epub 2006 Sep 15.},
	pages = {7438-44},
	type = {Journal Article},
	abstract = {For decades, untreated sewage flowing northward from Tijuana, Mexico, via the Tijuana River has adversely affected the water quality of the recreational beaches of San Diego, California. We used quantitative reverse transcription-PCR to measure the levels of hepatitis A virus (HAV) and enteroviruses in coastal waters near the United States-Mexico border and compared these levels to those of the conventional fecal indicators, Escherichia coli and enterococci. Over a 2-year period from 2003 to 2005, a total of 20 samples were assayed at two sites during both wet and dry weather: the surfzone at the mouth of the Tijuana River and the surfzone near the pier at Imperial Beach (IB), California (about 2 km north of the mouth of the Tijuana River). HAV and enterovirus were detected in 79 and 93\% of the wet-weather samples, respectively. HAV concentrations in these samples ranged from 105 to 30,771 viral particles/liter, and enterovirus levels ranged from 7 to 4,417 viral particles/liter. The concentrations of HAV and enterovirus were below the limit of detection for all dry weather samples collected at IB. Regression analyses showed a significant correlation between the densities of both fecal bacterial indicators and the levels of HAV (R2>0.61, P<0.0001) and enterovirus (R2>0.70, P<0.0001), a finding that supports the use of conventional bacterial indicators to predict the levels of these viruses in recreational marine waters.},
	keywords = {Base Sequence *Bathing Beaches California DNA, Complementary DNA, DNA United States, Viral/analysis Enterovirus/genetics/*isolation \& purification Environmental Monitoring/*methods Feces/*microbiology Hepatitis A virus/genetics/*isolation \& purification Mexico Molecular Sequence Data Organic Chemicals Reverse Transcriptase Polymerase Cha},
	issn = {0099-2240 (Print) 0099-2240 (Linking)},
	doi = {10.1128/AEM.01024-06},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/16980430},
	author = {Gersberg, R. M. and Rose, M. A. and Robles-Sikisaka, R. and Dhar, A. K.}
}
