

@article {15409,
	title = {The impact of a school-based hygiene, water quality and sanitation intervention on soil-transmitted helminth reinfection: a cluster-randomized trial},
	journal = {Am J Trop Med Hyg},
	volume = {89},
	number = {5},
	year = {Submitted},
	month = {Nov},
	pages = {875-83},
	abstract = {We conducted a cluster-randomized trial to assess the impact of a school-based water treatment, hygiene, and sanitation program on reducing infection with soil-transmitted helminths (STHs) after school-based deworming. We assessed infection with STHs at baseline and then at two follow-up rounds 8 and 10 months after deworming. Forty government primary schools in Nyanza Province, Kenya were randomly selected and assigned to intervention or control arms. The intervention reduced reinfection prevalence (odds ratio [OR] 0.56, 95\% confidence interval [CI] 0.31-1.00) and egg count (rate ratio [RR] 0.34, CI 0.15-0.75) of Ascaris lumbricoides. We found no evidence of significant intervention effects on the overall prevalence and intensity of Trichuris trichiura, hookworm, or Schistosoma mansoni reinfection. Provision of school-based sanitation, water quality, and hygiene improvements may reduce reinfection of STHs after school-based deworming, but the magnitude of the effects may be sex- and helminth species-specific.},
	keywords = {Adolescent, Animals, Ascariasis/epidemiology/parasitology/ transmission, Ascaris lumbricoides/isolation \& purification, Child, Female, Hookworm Infections/epidemiology/parasitology/ transmission, Humans, Hygiene/ education, Kenya/epidemiology, Male, prevalence, sanitation, Schistosoma mansoni/isolation \& purification, Schistosomiasis/epidemiology/parasitology/ transmission, Schools, Soil/parasitology, Trichuris/isolation \& purification, Water quality},
	isbn = {1476-1645 (Electronic)<br/>0002-9637 (Linking)},
	author = {Freeman, M. C. and Clasen, T. and Brooker, S. J. and Akoko, D. O. and Rheingans, R.}
}
