

@article {14933,
	title = {Detection of vaccine-derived polioviruses in {Mexico} using environmental surveillance},
	journal = {J Infect Dis},
	volume = {210 Suppl 1},
	year = {2014},
	month = {nov},
	pages = {S315{\textendash}23},
	abstract = {BACKGROUND: Early detection and control of vaccine-derived poliovirus (VDPV) emergences are essential to secure the gains of polio eradication. METHODS: Serial sewage samples were collected in 4 towns of Mexico before, throughout, and after the May 2010 oral poliovirus vaccine (OPV) mass immunization campaign. Isolation and molecular analysis of polioviruses from sewage specimens monitored the duration of vaccine-related strains in the environment and emergence of vaccine-derived polioviruses in a population partially immunized with inactivated poliovirus vaccine (IPV). RESULTS: Sabin strains were identified up to 5-8 weeks after the campaign in all towns; in Aguascalientes, 1 Sabin 3 was isolated 16 weeks after the campaign, following 7 weeks with no Sabin strains detected. In Tuxtla Gutierrez, type 2 VDPV was isolated from 4 samples collected before and during the campaign, and type 1 VDPV from 1 sample collected 19 weeks afterward. During 2009-2010, coverage in 4 OPV campaigns conducted averaged only 57\% and surveillance for acute flaccid paralysis (AFP) was suboptimal (AFP rate{\textbackslash}textless1 per 100,000 population{\textbackslash}textless15 years of age) in Tuxtla Gutierrez. CONCLUSIONS: VDPVs may emerge and spread in settings with inadequate coverage with IPV/OPV vaccination. Environmental surveillance can facilitate early detection in these settings.},
	keywords = {*Environmental Monitoring, Adolescent, Child, environmental surveillance, Female, Humans, inactivated poliovirus vaccine, Infant, Male, Mexico, Newborn, Oral/*administration \& dosage, polio, Poliovirus Vaccine, Poliovirus/classification/genetics/*isolation \& purification, Preschool, Sewage/*virology, Time Factors, vaccine-derived poliovirus},
	issn = {1537-6613 (Electronic) 0022-1899 (Linking)},
	doi = {10.1093/infdis/jiu183},
	author = {Esteves-Jaramillo, A. and Estivariz, C. F. and Penaranda, S. and Richardson, V. L. and Reyna, J. and Coronel, D. L. and Carrion, V. and Landaverde, J. M. and Wassilak, S. G. and Perez-Sanchez, E. E. and Lopez-Martinez, I. and Burns, C. C. and M A Pallansch}
}
