

@article {14533,
	title = {New generation of inactivated poliovirus vaccines for universal immunization after eradication of poliomyelitis},
	journal = {Clin Infect Dis},
	volume = {47},
	year = {2008},
	month = {dec},
	pages = {1587{\textendash}92},
	abstract = {Twenty years of global polio eradication efforts may soon eliminate the transmission of wild-type poliovirus. However, new information that has been learned about poliovirus, as well as the political realities of a modern world, demand that universal immunity against poliomyelitis be maintained, even after wild-type poliovirus is eradicated. Although 2 excellent vaccines have proven to be highly effective in the past, neither the live-attenuated vaccine nor the currently used inactivated vaccine are optimal for use in the posteradication era. Therefore, concerted efforts are urgently needed to develop a new generation of vaccine that is risk-free and affordable and can be produced on a global scale. Here, we discuss the desired properties of a vaccine and methods to create a new polio vaccine.},
	keywords = {Humans, Inactivated/*immunology, Poliomyelitis/*prevention \& control, Poliovirus Vaccine},
	issn = {1537-6591 (Electronic) 1058-4838 (Linking)},
	doi = {10.1086/593310},
	author = {Chumakov, K. and Ehrenfeld, E.}
}
