

@article {13946,
	title = {Virulence profiling and quantification of verocytotoxin-producing {Escherichia} coli {O}145:{H}28 and {O}26:{H}11 isolated during an ice cream-related hemolytic uremic syndrome outbreak.},
	journal = {Foodborne pathogens and disease},
	volume = {8},
	number = {3},
	year = {2011},
	month = {mar},
	pages = {421{\textendash}6},
	abstract = {In September-October 2007, a mixed-serotype outbreak of verocytotoxin-producing Escherichia coli (VTEC) O145:H28 and O26:H11 occurred in the province of Antwerp, Belgium. Five girls aged between 2 and 11 years developed hemolytic uremic syndrome, and seven other coexposed persons with bloody diarrhea were identified. Laboratory confirmation of O145:H28 infection was obtained for three hemolytic uremic syndrome patients, one of whom was coinfected with O26:H11. The epidemiological and laboratory investigations revealed ice cream as the most likely source of the outbreak. The ice cream was produced at a local dairy farm using pasteurized milk. VTEC of both serotypes with indistinguishable pulsed-field gel electrophoresis patterns were isolated from patients, ice cream, and environmental samples. Quantitative analysis of the ice cream indicated concentrations of 2.4 and 0.03 CFU/g for VTEC O145 and O26, respectively. Virulence typing revealed that the repertoire of virulence genes carried by the O145:H28 outbreak strain was comparable to that of O157 VTEC and more exhaustive as compared to the O26:H11 outbreak strain and nonrelated clinical strains belonging to these serotypes. Taken together, these data suggest that O145:H28 played the most important role in this outbreak.},
	issn = {1556-7125},
	doi = {10.1089/fpd.2010.0693},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/21166561},
	author = {Buvens, Glenn and Poss{\'e}, Bj{\"o}rn and De Schrijver, Koen and De Zutter, Lieven and Lauwers, Sabine and Pi{\'e}rard, Denis}
}
