

@article {1055,
	title = {Correlation between rotavirus A genotypes detected in hospitalized children and sewage samples in 2006, C{\'o}rdoba, Argentina.},
	journal = {Journal of medical virology},
	volume = {82},
	number = {7},
	year = {2010},
	pages = {1277-1281},
	abstract = {Routine rotavirus A {(RV-A)} surveillance is based on clinical cases, so only symptomatic infections are reported. The objective of this study was to determine whether the {RV-A} genotypes and cold seasonal pattern described in patients with diarrhea is reflected by sewage surveillance, which could be representative of the {RV-A} genotypes circulating in the population. The genotype distribution of {RV-A} in effluent samples from a local sewage treatment plant was compared to those from local clinical cases. A total of 52 sewage samples and 70 stool specimens from children with acute non-bacterial diarrhea were collected from January to December 2006. The effluent specimens were concentrated and {RNA} extracts from concentrated sewage and clinical samples were genotyped for the rotavirus {VP7} gene. The proportional distribution of the {RV-A} G-genotypes in sewage and clinical samples during the cold season was similar: G1 accounted for 26.6\% of the typed sewage isolates and 28.8\% of the clinical infections; G3 type accounted for 21.9\% and 25.8\%; G2 type 15.6\% and 10.6\%; G4 type 17.2\% and 21.2\%; G8 type 1.6\% and 0\%; and the G9 type 17.2\% and 13.6\%, respectively. A similar picture of {RV-A} genotype detection was obtained in sewage samples collected during the cold and warm seasons. The results indicate that there is a correlation between genotypes of {RV-A} isolates from human diarrheic patients and of those from sewage samples. In addition, sewage monitoring highlighted the uniform all-year {RV-A} circulation, which was in contrast to the peak incidence of {RV-A} infection in the community.},
	doi = {10.1002/jmv.21800},
	url = {http://dx.doi.org/10.1002/jmv.21800},
	author = {Barril, PA and Giordano, MO and Isa, MB and Masachessi, G and Ferreyra, LJ and Castello, AA and Glikmann, G and Nates, SV}
}
