

@article {10012,
	title = {{Viral load of human bocavirus-1 in stools from children with viral diarrhoea in Paraguay}},
	journal = {Epidemiology and Infection},
	volume = {141},
	number = {12},
	year = {2013},
	pages = {2576{\textendash}2580},
	abstract = {Since their discovery, four species of human bocavirus (HBoV) have been described in patients with respiratory and gastrointestinal diseases. However, a clear causal association between HBoV-1 and gastroenteritis has not been demonstrated. In this study, we describe the detection and quantification of HBoV-1 in stools from children with acute non-bacterial gastroenteritis using quantitative polymerase chain reaction. HBoV-1 genome was detected in 10{\textperiodcentered}6{\%} of stools with frequent association with rotavirus and norovirus. The median of HBoV-1 viral load was 1{\textperiodcentered}88{\texttimes}104 genome/ml, lower than previously shown in secretions of patients with respiratory infections, without any obvious association between high viral load and presence of HBoV as single agent. Thus, although HBoV-1 was frequently detected in these patients, there is no clear causal association of this agent with diarrhoea. Indeed, HBoV-1 DNA in stools of patients with gastroenteritis without respiratory symptoms may be a remnant of previous infections or associated with prolonged shedding of virus in the respiratory or digestive tracts},
	keywords = {d u c t, Gastroenteritis, hbov, Human bocavirus, i n t ro, i o n, meta-genomic study of pooled, Norovirus, rotavirus, specimens of respir-, viral co-infections, was discovered during a},
	issn = {0950-2688},
	doi = {10.1017/S095026881300023X},
	url = {http://www.journals.cambridge.org/abstract{\_}S095026881300023X},
	author = {Proenca-Modena, J L. and Martinez, M. and Amarilla, A. A. and Esp{\'\i}nola, E. E. and Galeano, M. E. and Fari{\~n}a, N. and RUSSOMANDO, G. and AQUINO, V. H. and PARRA, G. I. and ARRUDA, E.}
}
